ReliOn/Novolin R
R,Neutral by Novo Nordisk
short-acting r-DNA/GE/GM
U100 none
Line Novolin
Also known as Novolin R, Actrapid
Similar to  
Action in cats  
  • onset Xh,
  • peak Xh
  • duration Xh
Action in dogs  
  • onset 10-30 minutes,
  • peak 1-5h,
  • duration 4-10h[1]
Use and Handling
Type soluble
Shelf Life 24 months
When opened 28 days room temp.
In pen 28 days room temp.
  • protect from light and heat
  • Do Not Freeze
  • May be used intravenously

The insulin is made by Novo Nordisk for Wal-Mart/Sam's Club under the ReliOn brand name[2]. It is the same insulin from the same manufacturer as Novolin R and Actrapid[3][4][5][6].

The difference is in the price; the ReliOn branded insulins are cheaper in price but not in quality.

Like all R or neutral insulins, nothing is added (suspensions) to alter the insulin's action or speed[7]

Other comparable insulins are Humulin R[8], Humulin S[9][10][11], Insuman Rapid[12].


  1. Insulins-North American Veterinary Conference-2005
  2. Photo of ReliOn/Novolin insulins; ReliOn/Novolin R is at left
  3. Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Actrapid
  4. EMEA Scientific Discussion-Actrapid
  5. Prescribing Novo Insulins
  6. Prescribing Insuman Insulins
  7. FDA-Humulin R
  8. Humulin R Regular Human Insulin
  9. Electronic Medicines Compendium (EMC) UK Patient Information Leaflet-Humulin S
  10. Humulin S Prescribing Information
  11. Lilly EU/UK Product Sheet & Time Activity Profiles
  12. Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Insuman Rapid
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