ReliOn/Novolin 70/30
R/Neutral/NPH/Isophane Mix by Novo Nordisk
intermediate-acting r-DNA/GE/GM
U100 isophane
Line Novolin
Also known as Novolin 70/30, Mixtard 30. Actraphane 30/70, Penmix 30[1]
Similar to  
Action in cats  
  • onset Xh,
  • peak Xh
  • duration Xh
Action in dogs  
  • onset 0.5-3h,
  • peak 2-10h,
  • duration 4-24hh
Use and Handling
Type cloudy
Shelf Life 24 months
When opened 28 days room temp.
In pen 28 days room temp.

A mixed insulin, containing 30% R neutral and 70% NPH isophane  crystal insulin[2]. All ReliOn insulins are made by Novo Nordisk and are identical to those in their Novolin line[3].

The difference between Novolin 70/30, Actraphane 30/70, Mixtard 30[4][5][6][7] is only the ReliOn name added to the label and the less expensive price; they all come from Novo.

Other comparable insulins made by others are: Humulin 70/30[8] and Humulin M3[9][10][11].


  1. Medsafe NZ Penmix 30
  2. EMEA Scientific Discussion-Actraphane
  3. Photo of ReliOn/Novolin insulins; ReliOn/Novolin 70/30 is at right.
  4. EMEA Scientific Discussion-Mixtard
  5. Insulins & Mixtures
  6. Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Mixtard 30
  7. Prescribing Novo Insulins
  8. Humulin 70/30-NPH;R Human Insulin
  9. Electronic Medicines Compendium (EMC) UK Patient Information Leaflet-Humulin M3
  10. Humulin M3 Prescribing Information
  11. Lilly EU/UK Product Sheet & Time Activity Profiles
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