Protaphane | |
NPH/Isophane by Novo Nordisk | |
intermediate-acting | r-DNA/GE/GM |
U100 | Isophane |
Line | Novo |
Also known as | Novolin N, ReliOn/Novolin NPH, Insulatard |
Similar to | |
Action in cats | |
Action in dogs |
|
Use and Handling | |
---|---|
Type | cloudy |
Shelf Life | 30 months |
When opened | 6 weeks room temp. |
In pen | 6 weeks room temp. |
Notes |
|
Another Novo Nordisk name for its NPH/isophane insulin[4][5][6][7].
Technical details[]
This type of insulin tends to have an onset of 2-4 hours, a peak action of 4-10 hours, and a total duration of 10-20 hours, in humans.
These times seem to be similar in dogs, but considerably compressed in cats, possibly because of cats' faster metabolism.
Cats seem instead to experience a 1-2 hour onset, a peak action of 4-6 hours, and a total duration of 8-12 hours maximum, according to user surveys on Felinediabetes.com
It is a neutral suspension of isophane insulin crystals[8][9].
Those in North America know it as Novolin N; others call it Insulatard.
It is an intermediate-acting insulin[10] with more than one company producing this type.
Eli Lilly calls theirs Humulin N[11] [12] and Humulin I[13][14], while Aventis has its Insuman Basal[15][16].
Further Reading[]
References[]
- ↑ Insulins-North American Veterinary Conference-2005
- ↑ Selecting an Insulin for Treatment of Diabetes Mellitus in Dogs & Cats-Nelson-OSU Endocrinology Symposium 2006-Page 41
- ↑ Insulins-North American Veterinary Conference-2005
- ↑ EMEA Scientific Discussions-Protaphane
- ↑ APP Online Guide-Protaphane
- ↑ Novo Nordisk Australia-Protaphane
- ↑ Prescribing Novo Insulins
- ↑ EMEA Scientific Discussion-Insulatard
- ↑ Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Insulatard
- ↑ Diabetes New Zealand-Insulin
- ↑ US FDA-Humulin N
- ↑ Humulin N NPH/Isophane Human Insulin Remedyfind.com
- ↑ Humulin I Prescribing Information
- ↑ Electronic Medicines Compendium (EMC) UK-Patient Infrmation Leaflet-Humulin I
- ↑ Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Insuman Basal
- ↑ Insuman Prescribing Information