Diabetes in Pets
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Monotard Pork
Lente by Novo Nordisk
intermediate-acting Porcine
U100 Zinc
Line Novo
Also known as N/A
Similar to :
Action in cats  
  • onset Xh,
  • peak Xh
  • duration: Xh
Action in dogs  
  • onset <1h,
  • peak 4-8h,
  • duration 14-24h
Use and Handling
Type cloudy
Shelf Life 24 months
When opened 28 days
In pen N/A
Notes  
  • protect from light and heat
  • store at 2-8C
  • Do not use if product does not re-suspend
  • Roll
  • See Caninsulin/Vetsulin for current handling notes on pork lente insulin.

Monotard Pork was a U100, 100% porcine insulin made by Novo Nordisk. It was an intermediate-acting, lente-type. Eli Lilly also made a comparable pork lente insulin, Iletin II Lente[1][2]. As the other Lente insulins[3], it was a suspension of crystalline (ultralente) and amorphous (semilente) insulin in a ratio of 7 crystalline parts to 3 amorphous parts.

Monotard Pork was also identical to Caninsulin[4][5]/Vetsulin with the only exception being its strength: Pork Monotard was U100 strength, while Caninsulin/Vetsulin is U40.

No Lente-type insulin regardless of species can contain any NPH/isophane insulin[6] or any R/Neutral insulin[7]. Both are chemically impossible: the phenol preservative present in NPH/isophane alters the action of Lente-type insulins, creating a mixture with an approximate action of R/Neutral. The zinc suspension of Lente-type insulin binds R/Neutral, causing the short-acting insulin to slow, losing its short-acting effect[8][9].


References

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