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Monotard Pork was a U100, 100% porcine insulin made by [[Novo Nordisk]]. It was an intermediate-acting, lente-type. [[Eli Lilly]] also made a comparable pork lente insulin, [[Iletin II Lente]]. [http://www.emea.eu.int/humandocs/PDFs/EPAR/monotard/205602en6.pdf As] the other Lente insulins, it was a suspension of crystalline (ultralente) and amorphous (semilente) insulin in a ratio of 7 crystalline parts to 3 amorphous parts. |
Monotard Pork was a U100, 100% porcine insulin made by [[Novo Nordisk]]. It was an intermediate-acting, lente-type. [[Eli Lilly]] also made a comparable pork lente insulin, [[Iletin II Lente]]. [http://www.emea.eu.int/humandocs/PDFs/EPAR/monotard/205602en6.pdf As] the other Lente insulins, it was a suspension of crystalline (ultralente) and amorphous (semilente) insulin in a ratio of 7 crystalline parts to 3 amorphous parts. |
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| + | '''No''' Lente-type insulin regardless of species can contain any [[NPH]]/[[isophane]] insulin<ref>[http://www.nfb.org/vodold/vsum9809.htm Combining Lente-type Insulins with Phenol-Preserved Insulins]</ref> '''or''' any [[R]]/[[Neutral]] insulin<ref>[http://www.endotext.org/diabetes/diabetes17/diabetes17.htm Lente Zinc Suspension Causes Loss Of R/Neutral Short-Acting Effect]</ref>. Both are chemically impossible: the phenol [[preservatives|preservative]] present in [[NPH]]/[[isophane]] alters the action of Lente-type insulins, creating a mixture with an approximate action of [[R]]/[[Neutral]]. The zinc [[suspension]] of Lente-type insulin binds [[R]]/[[Neutral]], causing the [[short-acting]] insulin to slow, losing its short-acting effect. |
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| + | ==References== |
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| + | <references/> |
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[[Category:Insulins]][[Category:Lente]][[Category:intermediate-acting]][[Category:porcine]][[Category:Novo Nordisk]] |
[[Category:Insulins]][[Category:Lente]][[Category:intermediate-acting]][[Category:porcine]][[Category:Novo Nordisk]] |
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Revision as of 00:21, 4 July 2006
| Monotard Pork | |
| Lente by Novo Nordisk | |
| intermediate-acting | Porcine |
| U100 | Zinc |
| Line | Novo |
| Also known as | N/A |
| Similar to | :
|
| Action in cats |
|
| Action in dogs |
|
| Use and Handling | |
|---|---|
| Type | cloudy |
| Shelf Life | 24 months |
| When opened | 28 days |
| In pen | N/A |
| Notes |
|
Monotard Pork was a U100, 100% porcine insulin made by Novo Nordisk. It was an intermediate-acting, lente-type. Eli Lilly also made a comparable pork lente insulin, Iletin II Lente. As the other Lente insulins, it was a suspension of crystalline (ultralente) and amorphous (semilente) insulin in a ratio of 7 crystalline parts to 3 amorphous parts.
No Lente-type insulin regardless of species can contain any NPH/isophane insulin[1] or any R/Neutral insulin[2]. Both are chemically impossible: the phenol preservative present in NPH/isophane alters the action of Lente-type insulins, creating a mixture with an approximate action of R/Neutral. The zinc suspension of Lente-type insulin binds R/Neutral, causing the short-acting insulin to slow, losing its short-acting effect.