Mixtard 30
R/Neutral/NPH/Isophane Mix by Novo Nordisk
short-acting r-DNA/GE/GM
U100 isophane
Line Novo
Also known as Actraphane 30/70, Novolin 70/30, Penmix 30[1], ReliOn/Novolin 70/30
Similar to  
Action in cats  
  • onset Xh,
  • peak Xh
  • duration Xh
Action in dogs  
  • onset 0.5-3h,
  • peak 2-10h,
  • duration 4-24h
Use and Handling
Type cloudy
Shelf Life 30 months
When opened 6 weeks room temp.
In pen 6 weeks room temp.
  • protect from light and heat
  • Do Not Freeze
  • Do not use if product does not re-suspend
  • Roll
  • Do not use intravenously
  • Do not refrigerate in use cartridges/pens.

Mixtard 30 is Novo Nordisk's r-DNA/GE/GM human insulin mix[2][3] consisting of 30% R/neutral insulin and 70% NPH/isophane insulin crystals[4].

It is the same as Humulin 70/30[5].

Novo calls the same mix Novolin 70/30or ReliOn/Novolin 70/30 in North America.

A comparable insulin made by Eli Lilly is Humulin M3[6][7][8]; another by Novo is Actraphane 30/70[9] .


  1. Medsafe NZ Penmix 30
  2. Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Mixtard 30
  3. Prescribing Novo Insulins
  4. EMEA Scientific Discussion-Mixtard
  5. Humulin 70/30-NPH;R Human Insulin
  6. Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Humulin M3
  7. Humulin M3 Prescribing Information
  8. Lilly EU/UK Product Sheet & Time Activity Profiles
  9. EMEA Scientific Discussion Actraphane
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