Diabetes in Pets
Don't have an account?
Register
Register
in: Insulins, Mixed, Intermediate-acting,
and 6 more

Changes: Mixtard 20

Back to page
Sign in to edit
(adding Lilly EU/UK product sheet & TAPS/linking to Humulin M2 page)
No edit summary
 
(13 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
{{Insulin|
  
{{Insulin|
−
bgcolor=#906|
 +
bgcolor=#CCC|
−
fgcolor=#fd0|
 +
fgcolor=#0000|
 
name=Mixtard 20|
  
name=Mixtard 20|
 
generic=[[Mixed Insulins|R/Neutral/NPH/Isophane Mix]]|
  
generic=[[Mixed Insulins|R/Neutral/NPH/Isophane Mix]]|
Line 10: Line 10:
 
suspension=[[isophane]]|
  
suspension=[[isophane]]|
 
line=[[Novo Nordisk|Novo]]|
  
line=[[Novo Nordisk|Novo]]|
  +
aliases=[[Actraphane 20/80]], [[Penmix 20]]<ref>[http://www.medsafe.govt.nz/Profs/DataSheet/PenmixMixtardProtaphaneinj.htm Medsafe NZ Penmix 20]</ref>|
−
aliases=[[Actraphane 20/80]]|
  
 
similar=[[Humulin M2]]|
  
similar=[[Humulin M2]]|
 
cataction=&nbsp;
  
cataction=&nbsp;
Line 33: Line 33:
 
}}
  
}}
   
−
A mixed, intermediate-acting insulin<ref>[http://emc.medicines.org.uk/emc/assets/c/html/displaydoc.asp?documentid=3604 Electronic Medicines Compendium (EMC) UK-Patient Information-Mixtard 20]</ref><ref>[http://www.drgc.cwc.net/Care_pathway/Patient_information/Insulin/Novo_insulins.htm Prescribing Novo Insulins]</ref> made by [[Novo Nordisk]] containing 20% R/neutral insulin and 80% NPH/isophane insulin crystals<ref>[http://www.emea.eu.int/humandocs/PDFs/EPAR/mixtard/226802en6.pdf EMEA Scientific Discussion-Mixtard]</ref><ref>[http://www.remedyfind.com/treatments/0/1299/Insulin:%20Humulin%2020/80%20etc.%20(R%20Human;%20NPH%20Insulin) Humulin 20/80-NPH;R Human Insulin Remedyfind.com]</ref>. Comparable product is also made by Novo: [[Actraphane 20/80]]<ref>[http://www.emea.eu.int/humandocs/PDFs/EPAR/actraphane/504002en6.pdf EMEA Scientific Discussion-Actraphane]</ref>. Eli Lilly once produced a similar insulin in the EU & UK called [[Humulin M2]]<ref>[http://www.yorkshirediabetes.com/downloads/1071_LLY_Diabetes_RangeChar.pdf Lilly Product Sheet & Time Activity Profiles]</ref>; it was discontinued in July 2004<ref>[http://72.14.203.104/search?hl=en&q=cache:qy3YVLOZg0YJ:http://www.diabetes.org.uk/infocentre/inform/insulinwithdrawal2004.htm+humulin+uk Diabetes UK Google Cached Page-Withdrawal of Humulin M2 July 2004]</ref>.
 +
A mixed, intermediate-acting insulin<ref>[http://emc.medicines.org.uk/medicine/15974/XPIL/Mixtard+30+100+IU+ml++Suspension+for+Injection+in+a+vial/ Electronic Medicines Compendium (EMC) UK-Patient Information-Mixtard 20]</ref><ref>[http://www.drgc.cwc.net/Care_pathway/Patient_information/Insulin/Novo_insulins.htm Prescribing Novo Insulins]</ref> made by [[Novo Nordisk]] containing 20% R/neutral insulin and 80% NPH/isophane insulin crystals<ref>[http://www.emea.europa.eu/humandocs/PDFs/EPAR/mixtard/226802en6.pdf EMEA Scientific Discussion-Mixtard]</ref><ref>[http://www.remedyfind.com/treatments/0/1299/Insulin:%20Humulin%2020/80%20etc.%20(R%20Human;%20NPH%20Insulin) Humulin 20/80-NPH;R Human Insulin Remedyfind.com]</ref>.
  +
  +
Comparable product is also made by Novo: [[Actraphane 20/80]]<ref>[http://www.emea.europa.eu/humandocs/PDFs/EPAR/actraphane/504002en6.pdf EMEA Scientific Discussion-Actraphane]</ref>.
  +
  +
Eli Lilly once produced a similar insulin in the EU & UK called [[Humulin M2]]<ref>[http://www.yorkshirediabetes.com/downloads/1071_LLY_Diabetes_RangeChar.pdf Lilly Product Sheet & Time Activity Profiles]</ref>; it was discontinued in July 2004<ref>[http://www.pharmj.com/editorial/20040327/products/p379products.html Withdrawal of Humulin M2 July 2004]</ref>.
  +
  +
Mixtard 20 was discontinued December 31, 2007.<ref>[http://www.ukmicentral.nhs.uk/therapeu/pace/PACE0604.pdf Insulin Discontinuations-UK]</ref><ref>[http://www.yorkshirediabetes.com/downloads/A4Humandis.pdf Chart of Discontinued Novo Human Insulins]</ref>
   
 
==References==
  
==References==
 
<references/>
  
<references/>
   
−
[[Category:Insulins]][[Category:Mixed]][[Category:intermediate-acting]][[Category:Novo Nordisk]]
 +
[[Category:Insulins]][[Category:Mixed]][[Category:intermediate-acting]][[Category:Novo Nordisk]][[Category:Intravenous use NO]][[Category:Meta-cresol]][[Category:Phenol]][[Category:Isophane]][[Category:Phosphate]]

Latest revision as of 21:56, 25 June 2009

Mixtard 20
R/Neutral/NPH/Isophane Mix by Novo Nordisk
intermediate-acting r-DNA/GE/GM
U100 isophane
Line Novo
Also known as Actraphane 20/80, Penmix 20[1]
Similar to Humulin M2
Action in cats  
  • onset Xh,
  • peak Xh
  • duration Xh
Action in dogs  
  • onset 0.5-3h,
  • peak 2-10h,
  • duration 4-24h
Use and Handling
Type cloudy
Shelf Life 30 months
When opened 6 weeks room temp.
In pen 6 weeks room temp.
Notes  
  • protect from light and heat
  • Do Not Freeze
  • Do not use if product does not re-suspend
  • Roll
  • Do not use intravenously
  • Do not refrigerate in use pens/cartridges.

A mixed, intermediate-acting insulin[2][3] made by Novo Nordisk containing 20% R/neutral insulin and 80% NPH/isophane insulin crystals[4][5].

Comparable product is also made by Novo: Actraphane 20/80[6].

Eli Lilly once produced a similar insulin in the EU & UK called Humulin M2[7]; it was discontinued in July 2004[8].

Mixtard 20 was discontinued December 31, 2007.[9][10]

References

  1. ↑ Medsafe NZ Penmix 20
  2. ↑ Electronic Medicines Compendium (EMC) UK-Patient Information-Mixtard 20
  3. ↑ Prescribing Novo Insulins
  4. ↑ EMEA Scientific Discussion-Mixtard
  5. ↑ Humulin 20/80-NPH;R Human Insulin Remedyfind.com
  6. ↑ EMEA Scientific Discussion-Actraphane
  7. ↑ Lilly Product Sheet & Time Activity Profiles
  8. ↑ Withdrawal of Humulin M2 July 2004
  9. ↑ Insulin Discontinuations-UK
  10. ↑ Chart of Discontinued Novo Human Insulins
Community content is available under CC-BY-SA unless otherwise noted.