Hypurin Vet Protamine Zinc
PZI by CP Pharma
long-acting Bovine
U100 protamine
Line Hypurin
Also known as Hypurin Bovine Protamine Zinc, Hypurin Vet PZI, beef PZI
Similar to  
Action in cats  
  • onset 2-5h,
  • peak 12-24h
  • duration: maximum 36h
Action in dogs  
  • onset 2-5h,
  • peak 12-24h,
  • duration: maximum 36h-rarely used[1]
Use and Handling
Type cloudy
Shelf Life 36 months
When opened 28 days
In pen N/A

Hypurin Vet Protamine Zinc is a beef-based PZI insulin[2] made by CP Pharma[3].

It is approved only for veterinary use and for distribution within the UK -- from abroad you can only order the human-approved equivalent, Hypurin Bovine Protamine Zinc.

Insuvet Protamine Zinc is also 100% bovine, U100 PZI.

US-compounded BCP PZI and Summit's PZI U100 strength insulin is comparable to this one.

No Combining For PZI

Protamine Zinc PZI[4] insulin cannot be combined with other insulins, due to the amount of protamine in the insulin's formula[5][6].


  1. Insulins-North American Veterinary Conference
  2. Hypurin Bovine Protamine Zinc Patient Information
  3. Electronic Medicines Compendium (EMC) UK-Hypurin Bovine Protamine Zinc
  4. Excess Protamine in Protamine Zinc Insulin Formula
  5. Comparison of Injection Techniques for Soluble and Protamine Zinc Insulins in Diabetes Mellitus PubMed-Practitioner-1975
  6. British National Formulary (BNF)-Protamine Zinc Insulin (PZI) Binds to Soluble Insulin in Same Syringe
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