Hypurin Porcine Neutral
R,Neutral by CP Pharma
short-acting Porcine
U100 none
Line Hypurin
Also known as Hypurin Pork Regular, pork R, pork neutral
Similar to  
Action in cats  
  • onset Xh,
  • peak Xh
  • duration Xh
Action in dogs  
  • onset 30-60 minutes,
  • peak 2-4h,
  • duration 6-8h
Use and Handling
Type soluble
Shelf Life 36 months
When opened 28 days room temp.
In pen 28 days room temp.
  • protect from light and heat
  • Do Not Freeze
  • May be used intravenously
  • Do not refrigerate in use cartridges

Hypurin Porcine Neutral or Hypurin Pork Regular (Canadian brand name) is a pork-based short-acting insulin made by CP Pharma[2].

Eli Lilly's Iletin II R[3][4] was comparable; Novo Nordisk's Pork Actrapid[5][6][7][8] still is sold in Europe, but will be discontinued at the end of December 2007[9].

As with all R/neutral insulins, regardless of species, nothing has been added to alter the speed or action of the insulin[10][11]

Health Canada has approved this insulin, along with another pork product--Hypurin Porcine Isophane, known as Hypurin Pork Isophane or Hypurin Pork NPH in Canada. Both are currently available on the Canadian market without importation[12]. See wiki's CP Pharma page for more information regarding their Canadian availability.

Further ReadingEdit


Pharmacology of a U40 Porcine Lente Insulin Preparation in Diabetic Cats-Journal of Feline Medicine & Surgery-Rand & Martin-2001
Study finds Pork Actrapid--Pork R/Neutral suitable for intravenous use in cats.


  1. Response to Withdrawal of Novo Porcine Insulins-CP/Wockhardt UK
  2. Electronic Medicines Compendium (EMC) UK-Hypurin Porcine Neutral
  3. Iletin II R, etc. Regular Pork Insulin
  4. US-FDA Iletin II R Discontinuation Notice July 2005
  5. Pork Actrapid Patient Information
  6. Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Pork Actrapid
  7. Prescribing Porcine Insulin
  8. Prescribing Novo Animal Insulin
  9. Pork Actrapid Discontinuation Notice
  10. Hypurin Porcine Neutral Patient Information
  11. FDA-Humulin R
  12. IDDT International Hypurin Pork Canadian Information
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