Humulin I | |
NPH/Isophane by Eli Lilly | |
intermediate-acting | r-DNA/GE/GM |
U100 | Isophane |
Line | Humulin |
Also known as | Humulin N |
Similar to | |
Action in cats | |
Action in dogs |
|
Use and Handling | |
---|---|
Type | cloudy |
Shelf Life | 18 months |
When opened | 28 days room temp. |
In pen | 28 days room temp. |
Notes |
|
This is the Euro name for Lilly's isophane-suspension insulin[4]--the "I" an abbreviation for isophane[5][6].
Lilly makes the same insulin known as Humulin N[7] in North America[8].
Like all other isophane/protamine suspended insulins, it is a crystalline suspension with protamine.
Technical details[]
This type of insulin tends to have an onset of 2-4 hours, a peak action of 4-10 hours, and a total duration of 10-20 hours, in humans.
These times seem to be similar in dogs, but considerably compressed in cats, possibly because of cats' faster metabolism.
Cats seem instead to experience a 1-2 hour onset, a peak action of 4-6 hours, and a total duration of 8-12 hours maximum, according to user surveys on Felinediabetes.com.
Novo Nordisk also has their Novolin N, Protaphane and Insulatard[9][10][11][12] while Aventis has their Insuman Basal[13][14].
Further Reading[]
References[]
- ↑ Insulins-North American Veterinary Conference-2005
- ↑ Selecting an Insulin for Treatment of Diabetes Mellitus in Dogs & Cats-Nelson-OSU Endocrinology Symposium 2006-Page 41
- ↑ Insulins-North American Veterinary Conference-2005
- ↑ Humulin I Prescribing Information
- ↑ Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Humulin I
- ↑ Lilly UK Product Names & Time Activity Profiles
- ↑ Humulin N-NPH/Isophane Human Insulin Remedyfind.com
- ↑ FDA--Humulin N
- ↑ Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Insulatard
- ↑ EMEA Scientific Discussion-Insulatard
- ↑ Prescribing Novo Insulins
- ↑ EMEA Scientific Discussion-Protaphane
- ↑ Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Insuman Basal
- ↑ Insuman Prescribing Information