British National Formulary[1] defines them as: A sterile solution of insulin (i.e. bovine or porcine) or of human insulin; pH 6.6-8.0
Short acting insulins have been around a long time. The first insulin produced for treatment of diabetes was short-acting; there was no such thing as longer acting insulins until the mid 1930's when PZI came on the market. Until then, most diabetics had to rely on a series of shots to get them through each day.
Today short-acting insulin is used as bolus for meals, for blood glucose "corrections" or Boosters when bg's are running too high, and for diabetic emergencies. When a pet or person is hospitalized for a diabetic emergency, some type of short or rapid-acting insulin is given intravenously to bring blood glucose levels down quickly.
These short-acting insulins are used either by themselves as bolus or booster insulin or as Mixed Insulins, combined with NPH/isophane insulin.
With the exception of semilente, they can be injected or given intravenously. Semilente can't be used intravenously because it is a suspended, "cloudy" insulin. Semilente by itself has almost disappeared from the market.
Trade names:
|
Short Acting Insulins | |
|---|---|
| Hypurin Bovine Neutral Hypurin Vet Neutral | |
| Insuvet Neutral | |
| Iletin I R (No longer produced.) | |
| Hypurin Porcine Neutral Hypurin Pork Regular | |
| Pork Actrapid (No longer produced.) | |
| Iletin II R (No longer produced.) | |
| Novo Semilente MC Note: Semilente insulin is not soluble. It cannot be used intravenously. (No longer produced.) | |
| Humulin R, Humulin S The "S" in the name stands for soluble, not semilente. | |
| Insuman Rapid | |
| Novolin R, Actrapid, ReliOn/Novolin R | |
Insulin analogs can be found under the Category:Fast-acting.
References[]
Case studies[]
Wiki cases-Feline Short-Acting Insulin Users
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