Actraphane 20/80

Use and Handling
Actraphane 20/80
R/Neutral/NPH/Isophane Mix by Novo Nordisk
intermediate-acting	r-DNA/GE/GM
U100	isophane
Line	Novo
Also known as	Mixtard 20,Penmix 20
Similar to	Humulin M2^[1]
Action in cats	onset Xh, peak Xh duration Xh
Action in dogs	onset 0.5-3h, peak 2-10h, duration 4-24h
Type	cloudy
Shelf Life	30 months
When opened	6 weeks room temp.
In pen	6 weeks room temp.
Notes	protect from light and heat Do Not Freeze Do not use if product does not re-suspend Roll Do not use intravenously

Novo Nordisk's brand name for its 20% R/neutral and 80% NPH/isophane crystal^[2] insulin^[3] which is intermediate-acting.

Insulins
Intermediate-acting
Mixed
7 more
Novo Nordisk
R-DNA/GE/GM
Intravenous use NO
Meta-cresol
Isophane
Phenol
Phosphate

Another comparable insulin, also Novo-made was Mixtard 20^[4]^[5]^[6]^[7]. Eli Lilly produced a comparable insulin called Humulin M2^[8]; it was discontinued in the EU & UK in July, 2004.

References[]

[1] Humulin M2 Discontinued July 2004

[2] EMEA Scientific Discussion Actraphane

[3] Humulin 20/80-NPH;R Human Insulin Remedyfind.com

[4] Electronic Medicines Compendium (EMC) UK-Patient Information Leaflet-Mixtard 20

[5] Insulins & Mixtures

[6] EMEA Scientific Discussion-Mixtard

[7] Prescribing Novo Insulins

[8] Lilly EU/UK Product Names & Time Activity Profiles

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